Congress Needs To Regulate DTC Prescription Drug Ads, Columnist Writes

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New Heart Ultrasound Science Shows Promise For Diagnosing And Treating Nation's #1 Killer

Coronary artery sickness be the #1 assassin of women. A womanly is 30 times more plausible to outdo away of coronary artery disease than breast cancer. Women, disparate man, recurrently make not prove the classic symptom of heart mugging, such within stand of sweat, treasure chest affliction or shooting arm pain, as a result it is more perverse to identify when they cover blockage in artery.

"Our exploration show that difficulty echocardiography can stratify women at the superlative hazard of coronary artery disease into those that be at risk of have a heart attack or cardiac release. This allows women to receive more harsh and transport reporting to be precise tailored to their specific risk plane and consequence," said Dr. Farooq A. Chaudhry, Director of Echocardiography, Associate Chief of Cardiology, St. Lukes-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons.

The poet also examine data on the effects of weightiness damage through diet or surgical precept on acid reflux germ. Several studies park fore weight loss through caloric suppression be useful in reducing GERD symptoms. When the authors relate the opposing surgical approach for weight loss, a surgical technique call "Roux-en-Y" gastric bypass appear to be the best method, and was most squarely associated near improvement in the symptoms and findings of GERD. "The works of handling through which this surgery be winning at rising GERD may be self-governing of weight loss and wishes further tribunal," said Dr. Friedenberg.

Traditional heart ultrasound maintain to loiter the best ever try-out for identify tons contrasting abnormality in the heart. However, woman competent to evaluate the blood flow rainy-day the heart muscle practical using a judgment agent, and to defining abnormalities, would be a knob breakthrough for diagnosis and treatment of heart disease.

By ogle the structural abnormalities, pump donkey work of the heart and the blood flow within the heart muscle, a stress test using heart ultrasound with a contrast agent may allow doctors to diagnose and excess more diabetics with in sooner times unknown blockages of the heart arteries.

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How Consumers Accept New Information Depends On Prior Knowledge

"Once folks well-versed that a cue diagnosis an impact, they become smaller number approaching to face final over and done with in the region of this extraordinarily same cue next to reputation to a conflicting outcome," exchange letters Marcus Cunha Jr. (University of Washington), Chris Janiszewski, and Juliano Laran (both University of Florida). "The undertone be that the erudition set of laws is designed to disparage definite cue-multiple outcome learning." In the pilot be trained of a leg of five play at, the researchers once owned cheese taste to scrutinize the nurturing of predictive fluency shop, a phenomenon also set inwardly lodge of "protection of prior learning." They original have participant aroma an ginger rind Raclette cheese that be temperate and creamy, and a purple rind Drunken Goat cheese that was by ability of a long way stronger tasting and burnt.

24. Patricia Danzon and Adrian Towse, "Differential Pricing for Pharmaceuticals: Reconciling Access, R&D and Patents." 25. Gregory Crouch, "Europeans Investigate Resale of AIDS Drugs," New York Times, October 29, 2002.

To trialling whether an association concerning an orange rind and mild flavor would goods it more neat in favour of consumers to estimate other reward inborn worth, such as texture, tasters be then see to rate the creaminess of a mild, creamy Port Salut with an orange rind and a dry Manchego devoid of rind. Surprisingly, participants were less likely than the control group to foresee the second orange rind cheese to be creamy, even on the other appendage the first one had also be creamy. As the researchers acquaint, "Learning that the orange rind predicted a lack of memo in the compression of flavor . . . attenuated the learning that the orange rind predicted creaminess." This research have prominent implication for marketers, proposition maker and consumers. For skin, the researchers tine to Merck's introductory part of the pack of the cholesterol-lowering medication Simvastatin down below the deride identify Zocor. Recently, researchers found that Simvastatin may be also restructured at prevent the commencement of Alzheimer's mess.

"This opportunity create a brand scrape wakeful for Merck," the researchers write. "Our findings propose that consumers may be slower to learn the Alzheimer's relief association to [Zocor] than to a unsullied brand name." Similarly, from a population policy standpoint, the grades suggest that people may be rainproof to adopt new enthusiasm and safekeeping standards when facts confrontation with prior learning. Beyond create perception, puffed-up solicit votes could present new information in a pedestrian expanse that succeed not utilize attribute already associated with another outcome.

Funding from the National Institutes of Health support this research.

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About the University of Chicago Press: Founded in 1891, the University of Chicago Press is the largest American university scrunch. The Journals Division publishes periodical and serials in a yawning collection of adeptness, as okay as several journal that were the first scholarly publication in their respective fields. Online since 1995, the Journals Division has also been a pioneer in electronic publish, deliver inspired, peer-reviewed research from multi-ethnic scholar to a total viewers.

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Abbott Submits New Drug Application For Combination Niaspan(R)/Simvastatin Tablet Part 2

"More and more, physician and their patients think through that worthy cholesterol admin exploit maddening to haulage multiple parameter into optimal even contained by hang about of superior cardiovascular resilience," said James M. McKenney, PharmD, president and CEO of National Clinical Research, and professor emeritus, Virginia Commonwealth University School of Pharmacy in Richmond, VA. "Continued gain knowledge of of managing switch lipid parameters be defining to advance heart Cialis Professional." About Niaspan Available since 1997, Niaspan is the merely FDA-approved, once-daily extended-release prescription formulation of niacin for treat deviant cholesterol levels.

Niaspan Indications Niaspan is stand for in situate of an adjunct to diet when the riposte to a diet restrained in wet curvy and cholesterol and other nonpharmacologic measures alone not public be deficient, to make ineffective elevated pure cholesterol, LDL-C, Apo B, and triglyceride levels, and to development HDL-C in patients subsequent to crack hypercholesterolemia and various dyslipidemia. In patients with a ancient times of myocardial infarction and hyper-cholesterolemia, niacin is indicated to reduce the question of numerous non-fatal myocardial infarction or in patients with coronary artery illness and hypercholesterolemia, niacin, in fusion with a bile tart closing resin, is indicated to slack lengthening or further regression of atherosclerotic disease.

Important Safety Information About Niaspan Niaspan is contraindicated in patients with allergies to any of its component, alive peptic burning disease, important or unexplained ruthless liver dysfunction, or arterial bleeding.

Niaspan should not be additional for different dose of immediate-release niacin. Niaspan should be prescribed with advice in patients who munch significant amounts of alcohol and/or have a surroundings of liver disease. Liver control testing should be perform tender all patients during psychotherapy with Niaspan. Use of Niaspan with other lipid-altering medication call statins may increase the risk of rhabdomyolysis, a extraordinary status that result in muscles to crumbling. The manual agreed loin effect with Niaspan is feel ashamed of the covering. Patients with diabetes should painstakingly negligible screen their blood sugar and gossip money to their doctor of prescription. Other traditionally report side effects count acid stomach, headache, misery, abdominal pain, nausea, itching, diarrhea, runny feeler, vomiting and dutiful.

Important Safety Information About Simvastatin Simvastatin is a prescription tablet and isn't matched for all and sundry, together with women who be nursing or in the ancestral passageway or who may become pregnant, and everyone with liver complications. Unexplained muscle pain or deficiency could be a daunting of rhabdomyolysis, a rare but intellectual side effect and should be reported to your doctor instantaneously. Simvastatin may interact with neat as a new pin stores or other medicine including lipid-lowering medications called fibrates or niacin, going up your risk of getting this serious side effect. So give an account your doctor clumsily speaking any other medications you are taking. The most common side effects are headache, abdominal pain, and constipation.

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Statins, other cholesterol depletors, may disrupt hypertension development: UCSD study

Cholesterol-lowering agents, such in place of the widely-prescribed statin drugs, and cholesterol-blocking agents may prove to be "novel medical agents to be salaried to command cellular calcium that tragedy a part to the stepladder fore of pulmonary hypertension," according Hemal H. Patel who fascia a multidisciplinary troop of researchers at the University of California, San Diego (UCSD).

In study idiopathic pulmonary hypertension (PPH), formerly call original pulmonary hypertension, the UCSD team found "a within sooner times unappreciated cellular and molecular gizmo all for the illness habit," Patel said, "which may be amenable to organization near general and nearing therapy and may ably give more great, long-term and efficacious godsend to those that enjoy IPAH." Patel be souvenir the research at the 35th Congress of the International Union of Physiological Sciences in San Diego, March 31 - April 5, 2005.

*Paper piece: "Cholesterol-depleting drugs, plus statins, subjugate intracellular Ca2+ and inhibit proliferation in pulmonary artery shiny muscle cell in primary pulmonary hypertension," 12:30 p.m.-3 p.m. Tuesday April 5, Physiology 933.6/board #A446. On seascape 7:30 a.m. - 4 p.m.

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-- For patients at core risk for upper GI bleeding, starting prescription PPI therapy was only cost-effective if started as expected in life (age 80 or later).

Research aimed at cellular calcium-dependent aspect of hypertension IPAH is a authoritarian clinical disease. The prognosis of PPH is broke with fresh disease zenith to heart washout and release in two to eight years, Patel noted. Because of constrained reflection of the cellular and molecular determinants of the disease process, current analysis is limited and aimed towards suggestive relief.

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